Any vampire below 7th generation requires staff approval.
Any changing breed that is not of the twelve original Garou tribes requires staff approval.
Any city-wide (or especially state, country, or world-wide) event must go through staff.
There is no requirement to approve for your character being killed if it is what would "realistically" happen.
No more Hermit or Wayward Hunters will be approved unless you have a particularly compelling reason as to why it should be so.
Only Lucifer/Dave can approve any and all Vanguard characters. It is not an open organization, and the world, both mortal and immortal, is not yet aware of their existence save for a handful of people.